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Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis

ATP-binding cassette transporters A1 (ABCA1) and G1 (ABCG1) play a vital role in promoting cholesterol efflux. Although, the dysregulation of these transporters was attributed as one of the mechanisms of atherogenesis, what renders their dysfunction is not well explored. Previously, we have reported...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Differ
Hoofdauteurs: Boro, Monoranjan, Govatati, Suresh, Kumar, Raj, Singh, Nikhlesh K., Pichavaram, Prahalathan, Traylor, James G., Orr, A. Wayne, Rao, Gadiparthi N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862243/
https://ncbi.nlm.nih.gov/pubmed/32968199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00623-9
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