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Cholesterol crystals promote endothelial cell and monocyte interactions via H(2)O(2)-mediated PP2A inhibition, NFκB activation and ICAM1 and VCAM1 expression
In the present study, we show that cholesterol crystals induce NFκB activation, and ICAM1 and VCAM1 expression via xanthine oxidase-mediated H(2)O(2) production and PP2A inhibition in influencing endothelial cell and monocyte interactions and all these adverse effects of cholesterol crystals could b...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477634/ https://ncbi.nlm.nih.gov/pubmed/31022672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101180 |
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