X-linked cellular mosaicism underlies age-dependent occurrence of seizure-like events in mouse models of CDKL5 deficiency disorder

CDKL5 deficiency disorder (CDD) is an infantile epileptic encephalopathy presenting with early-onset seizures, intellectual disability, motor impairment, and autistic features. The disorder has been linked to mutations in the X-linked CDKL5, and mouse models of the disease recapitulate several aspec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Terzic, Barbara, Cui, Yue, Edmondson, Andrew C., Tang, Sheng, Sarmiento, Nicolas, Zaitseva, Daria, Marsh, Eric D., Coulter, Douglas A., Zhou, Zhaolan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856307/
https://ncbi.nlm.nih.gov/pubmed/33197557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105176
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados