Development of CAR T Cells Expressing a Suicide Gene Plus a Chimeric Antigen Receptor Targeting Signaling Lymphocytic-Activation Molecule F7

Chimeric antigen receptors (CARs) are fusion proteins that contain antigen-recognition domains and T cell signaling domains. Signaling lymphocytic-activation molecule F7 (SLAMF7) is a promising target for CAR T cell therapies of the plasma cell malignancy multiple myeloma (MM) because SLAMF7 is expr...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Amatya, Christina, Pegues, Melissa A., Lam, Norris, Vanasse, Danielle, Geldres, Claudia, Choi, Stephanie, Hewitt, Stephen M., Feldman, Steven A., Kochenderfer, James N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2021
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854354/
https://ncbi.nlm.nih.gov/pubmed/33129371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.10.008
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items