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Improving Therapy of Chronic Lymphocytic Leukemia (CLL) with Chimeric Antigen Receptor (CAR) T Cells

Adoptive cell immunotherapy for the treatment of chronic lymphocytic leukemia (CLL) has heralded a new era of synthetic biology. The infusion of genetically-engineered, autologous chimeric antigen receptor (CAR) T cells directed against CD19 expressed by normal and malignant B cells represents a nov...

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Detalhes bibliográficos
Publicado no:Semin Oncol
Main Authors: Fraietta, Joseph A., Schwab, Robert D., Maus, Marcela V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824551/
https://ncbi.nlm.nih.gov/pubmed/27040708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2016.02.006
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