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Chimeric Antigen Receptor (CAR)-Engineered Lymphocytes for Cancer Therapy

INTRODUCTION: Chimeric antigen receptors (CARs) usually combine the antigen binding site of a monoclonal antibody with the signal activating machinery of a T cell, freeing antigen recognition from major histocompatibility complex restriction and thus breaking one of the barriers to more widespread a...

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Bibliografiske detaljer
Main Authors: Ramos, Carlos A., Dotti, Gianpietro
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107373/
https://ncbi.nlm.nih.gov/pubmed/21463133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2011.573476
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