Hemoglobin switching in mice carrying the Klf1Nan variant

Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia IV (CDA-IV) (OMIM 613673) is associated with the...

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Publicat a:Haematologica
Autors principals: Korporaal, Anne, Gillemans, Nynke, Heshusius, Steven, Cantu, Ileana, van den Akker, Emile, van Dijk, Thamar B., von Lindern, Marieke, Philipsen, Sjaak
Format: Artigo
Idioma:Inglês
Publicat: Fondazione Ferrata Storti 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849558/
https://ncbi.nlm.nih.gov/pubmed/32467144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.239830
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