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Fetal globin expression is regulated by Friend of Prmt1

An estimated 6% to 7% of the earth's population carries a mutation affecting red blood cell function. The β-thalassemias and sickle cell disease are the most common monogenic disorders caused by these mutations. Increased levels of γ-globin ameliorate the severity of these diseases because feta...

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Autors principals: van Dijk, Thamar Bryn, Gillemans, Nynke, Pourfarzad, Farzin, van Lom, Kirsten, von Lindern, Marieke, Grosveld, Frank, Philipsen, Sjaak
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993632/
https://ncbi.nlm.nih.gov/pubmed/20688955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-274399
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