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Transfusion-independent β(0)-thalassemia after bone marrow transplantation failure: proposed involvement of high parental HbF and an epigenetic mechanism

Currently, bone marrow transplantation is the only curative treatment for β-thalassemia and sickle cell disease. In rare cases, sustained and full fetal hemoglobin production was observed in patients after failure of bone marrow transplantation. This rendered the patients transfusion-free, despite g...

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Библиографические подробности
Главные авторы: Paciaroni, Katia, Lucarelli, Guido, Martelli, Fabrizio, Migliaccio, Anna Rita, von Lindern, Marieke, Borg, Joseph, Gillemans, Nynke, van Dijk, Thamar B, Philipsen, Sjaak
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165118/
https://ncbi.nlm.nih.gov/pubmed/25232502
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