CNTO 530 Increases Expression of HbA and HbF in Murine Models of β-Thalassemia and Sickle Cell Anemia

CNTO 530 is an erythropoietin receptor agonist MIMETIBODY(TM) construct. CNTO 530 has been shown to be active in a number of rodent models of acquired anemia (e.g. renal insufficiency and chemotherapy induced anemia). We investigated the efficacy of CNTO 530 in murine models of β-thalassemia and sic...

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Detalhes bibliográficos
Main Authors: Makropoulos, Dorie A, Achuthanandam, Ram, Avery, Justin, Wilson, Krista, Brosnan, Kerry, Miller, Andrew, Nesspor, Thomas, Chroscinski, Denise, Walker, Mindi, Egenolf, Devon, Huang, ChiChi, Bugelski, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613800/
https://ncbi.nlm.nih.gov/pubmed/23157711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920113805219449
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