Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling

Genetic engineering of induced pluripotent stem cells (iPSCs) holds great promise for gene and cell therapy as well as drug discovery. However, there are potential concerns regarding the safety and control of gene expression using conventional vectors such as viruses and plasmids. Although human art...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Kazuki, Yasuhiro, Uno, Narumi, Abe, Satoshi, Kajitani, Naoyo, Kazuki, Kanako, Yakura, Yuwna, Sawada, Chiaki, Takata, Shuta, Sugawara, Masaki, Nagashima, Yuichi, Okada, Akane, Hiratsuka, Masaharu, Osaki, Mitsuhiko, Ferrari, Giulia, Tedesco, Francesco Saverio, Nishikawa, Satoshi, Fukumoto, Ken, Takayanagi, Shin-ichiro, Kunisato, Atsushi, Kaneko, Shin, Oshimura, Mitsuo, Tomizuka, Kazuma
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819819/
https://ncbi.nlm.nih.gov/pubmed/33552683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.12.012
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