Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

Human artificial chromosome (HAC) has several advantages as a gene therapy vector, including stable episomal maintenance that avoids insertional mutations and the ability to carry large gene inserts including the regulatory elements. Induced pluripotent stem (iPS) cells have great potential for gene...

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Detalhes bibliográficos
Main Authors: Kazuki, Yasuhiro, Hiratsuka, Masaharu, Takiguchi, Masato, Osaki, Mitsuhiko, Kajitani, Naoyo, Hoshiya, Hidetoshi, Hiramatsu, Kei, Yoshino, Toko, Kazuki, Kanako, Ishihara, Chie, Takehara, Shoko, Higaki, Katsumi, Nakagawa, Masato, Takahashi, Kazutoshi, Yamanaka, Shinya, Oshimura, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839293/
https://ncbi.nlm.nih.gov/pubmed/19997091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.274
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