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Shuttling of Peptide‐Drug Conjugates by G Protein‐Coupled Receptors Is Significantly Improved by Pulsed Application
G protein‐coupled receptors (GPCRs) can be used to shuttle peptide‐drug conjugates into cells. But, for efficient therapy, a high concentration of cargo needs to be delivered. To explore this, we studied the pharmacologically interesting neuropeptide Y(1) receptor (Y(1)R) in one recombinant and thre...
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| Izdano u: | ChemMedChem |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7818256/ https://ncbi.nlm.nih.gov/pubmed/32700391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000490 |
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