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Structural Model of Ghrelin Bound to its G Protein-Coupled Receptor

The peptide ghrelin targets the growth hormone secretagogue receptor 1a (GHSR) to signal changes in cell metabolism and is a sought-after therapeutic target, although no structure is known to date. To investigate the structural basis of ghrelin binding to GHSR, we used solid-state nuclear magnetic r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Structure
मुख्य लेखकों: Bender, Brian Joseph, Vortmeier, Gerrit, Ernicke, Stefan, Bosse, Mathias, Kaiser, Anette, Els-Heindl, Sylvia, Krug, Ulrike, Beck-Sickinger, Annette, Meiler, Jens, Huster, Daniel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992119/
https://ncbi.nlm.nih.gov/pubmed/30686667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.12.004
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