UFMylation inhibits the proinflammatory capacity of interferon-γ–activated macrophages

Macrophages activated with interferon-γ (IFN-γ) in combination with other proinflammatory stimuli, such as lipopolysaccharide or tumor necrosis factor-α (TNF-α), respond with transcriptional and cellular changes that enhance clearance of intracellular pathogens at the risk of damaging tissues. IFN-γ...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Balce, Dale R., Wang, Ya-Ting, McAllaster, Michael R., Dunlap, Bria F., Orvedahl, Anthony, Hykes, Barry L., Droit, Lindsay, Handley, Scott A., Wilen, Craig B., Doench, John G., Orchard, Robert C., Stallings, Christina L., Virgin, Herbert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817147/
https://ncbi.nlm.nih.gov/pubmed/33372156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011763118
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