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γ-Interferon-inducible Lysosomal Thiol Reductase (GILT) Maintains Phagosomal Proteolysis in Alternatively Activated Macrophages

Although it is known that lysosomal cysteine cathepsins require a reducing environment for optimal activity, it is not firmly established how these enzymes are maintained in their reduced-active state in the acidic and occasionally oxidative environment within phagosomes and lysosomes. γ-Interferon-...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Balce, Dale R., Allan, Euan R. O., McKenna, Neil, Yates, Robin M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231668/
https://ncbi.nlm.nih.gov/pubmed/25253686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.584391
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