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Role of the C-terminal propeptide in the activity and maturation of γ-interferon-inducible lysosomal thiol reductase (GILT)

γ-Interferon-inducible lysosomal thiol reductase (GILT) is constitutively expressed in antigen-presenting cells. GILT facilitates unfolding of endocytosed antigens in MHC class II-containing compartments by enzymatically reducing disulfide bonds. The enzyme is synthesized as a 35-kDa precursor. Alth...

詳細記述

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書誌詳細
主要な著者: Phan, Uyen T., Lackman, Rebecca L., Cresswell, Peter
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC129439/
https://ncbi.nlm.nih.gov/pubmed/12198183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182430499
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