Role of the C-terminal propeptide in the activity and maturation of γ-interferon-inducible lysosomal thiol reductase (GILT)

γ-Interferon-inducible lysosomal thiol reductase (GILT) is constitutively expressed in antigen-presenting cells. GILT facilitates unfolding of endocytosed antigens in MHC class II-containing compartments by enzymatically reducing disulfide bonds. The enzyme is synthesized as a 35-kDa precursor. Alth...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Phan, Uyen T., Lackman, Rebecca L., Cresswell, Peter
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2002
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198183/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.182430499
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!