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Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner

The level of proteolysis within phagosomes of dendritic cells (DCs) is thought to be tightly regulated, as it directly impacts the cell's efficiency to process antigen. Activity of the antimicrobial effector NADPH oxidase (NOX2) has been shown to reduce levels of proteolysis within phagosomes o...

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Detalles Bibliográficos
Main Authors: Rybicka, Joanna M, Balce, Dale R, Chaudhuri, Sibapriya, Allan, Euan R O, Yates, Robin M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280544/
https://ncbi.nlm.nih.gov/pubmed/22157818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.440
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