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Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner
The level of proteolysis within phagosomes of dendritic cells (DCs) is thought to be tightly regulated, as it directly impacts the cell's efficiency to process antigen. Activity of the antimicrobial effector NADPH oxidase (NOX2) has been shown to reduce levels of proteolysis within phagosomes o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280544/ https://ncbi.nlm.nih.gov/pubmed/22157818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.440 |
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