Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner

The level of proteolysis within phagosomes of dendritic cells (DCs) is thought to be tightly regulated, as it directly impacts the cell's efficiency to process antigen. Activity of the antimicrobial effector NADPH oxidase (NOX2) has been shown to reduce levels of proteolysis within phagosomes o...

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Bibliographic Details
Main Authors: Rybicka, Joanna M, Balce, Dale R, Chaudhuri, Sibapriya, Allan, Euan R O, Yates, Robin M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280544/
https://ncbi.nlm.nih.gov/pubmed/22157818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.440
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