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Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner

The level of proteolysis within phagosomes of dendritic cells (DCs) is thought to be tightly regulated, as it directly impacts the cell's efficiency to process antigen. Activity of the antimicrobial effector NADPH oxidase (NOX2) has been shown to reduce levels of proteolysis within phagosomes o...

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Autors principals: Rybicka, Joanna M, Balce, Dale R, Chaudhuri, Sibapriya, Allan, Euan R O, Yates, Robin M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280544/
https://ncbi.nlm.nih.gov/pubmed/22157818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.440
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