NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

The phagocyte NADPH oxidase (NOX2) is critical for the bactericidal activity of phagocytic cells and plays a major role in innate immunity. We showed recently that NOX2 activity in mouse dendritic cells (DCs) prevents acidification of phagosomes, promoting antigen cross-presentation. Inorder to inve...

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Detalhes bibliográficos
Main Authors: Mantegazza, Adriana R., Savina, Ariel, Vermeulen, Mónica, Pérez, Laura, Geffner, Jorge, Hermine, Olivier, Rosenzweig, Sergio D., Faure, Florence, Amigorena, Sebastián
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Phagocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597138/
https://ncbi.nlm.nih.gov/pubmed/18682599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134791
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