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Autonomous phagosomal degradation and antigen presentation in dendritic cells

Phagocytosis plays a critical role in both innate and adaptive immunity. Phagosomal fusion with late endosomes and lysosomes enhances proteolysis, causing degradation of the phagocytic content. Increased degradation participates in both innate protection against pathogens and the production of antig...

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Detalhes bibliográficos
Main Authors: Hoffmann, Eik, Kotsias, Fiorella, Visentin, Géraldine, Bruhns, Pierre, Savina, Ariel, Amigorena, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437883/
https://ncbi.nlm.nih.gov/pubmed/22908282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203912109
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