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Autonomous phagosomal degradation and antigen presentation in dendritic cells

Phagocytosis plays a critical role in both innate and adaptive immunity. Phagosomal fusion with late endosomes and lysosomes enhances proteolysis, causing degradation of the phagocytic content. Increased degradation participates in both innate protection against pathogens and the production of antig...

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Bibliografiske detaljer
Main Authors: Hoffmann, Eik, Kotsias, Fiorella, Visentin, Géraldine, Bruhns, Pierre, Savina, Ariel, Amigorena, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437883/
https://ncbi.nlm.nih.gov/pubmed/22908282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203912109
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