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Autonomous phagosomal degradation and antigen presentation in dendritic cells

Phagocytosis plays a critical role in both innate and adaptive immunity. Phagosomal fusion with late endosomes and lysosomes enhances proteolysis, causing degradation of the phagocytic content. Increased degradation participates in both innate protection against pathogens and the production of antig...

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Bibliografske podrobnosti
Main Authors: Hoffmann, Eik, Kotsias, Fiorella, Visentin, Géraldine, Bruhns, Pierre, Savina, Ariel, Amigorena, Sebastian
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437883/
https://ncbi.nlm.nih.gov/pubmed/22908282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203912109
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