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NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes

The phagosomal lumen in macrophages is the site of numerous interacting chemistries that mediate microbial killing, macromolecular degradation, and antigen processing. Using a non-hypothesis-based screen to explore the interconnectivity of phagosomal functions, we found that NADPH oxidase (NOX2) neg...

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Bibliografski detalji
Glavni autori: Rybicka, Joanna M., Balce, Dale R., Khan, Morgan F., Krohn, Regina M., Yates, Robin M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890838/
https://ncbi.nlm.nih.gov/pubmed/20498052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914867107
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