Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

Innate and adaptive immune responses that prime myeloid cells, such as macrophages, protect against pathogens(1,2). However, if left uncontrolled, these responses may lead to detrimental inflammation(3). Thus macrophages, particularly those resident in tissues, must remain quiescent in between infec...

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I publikationen:Nat Microbiol
Huvudupphovsmän: Wang, Ya-Ting, Zaitsev, Konstantin, Lu, Qun, Li, Shan, Schaiff, W. Timothy, Kim, Ki-Wook, Droit, Lindsay, Wilen, Craig B., Desai, Chandni, Balce, Dale R., Orchard, Robert C., Orvedahl, Anthony, Park, Sunmin, Kreamalmeyer, Darren, Handley, Scott A., Pfeifer, John D., Baldridge, Megan T., Artyomov, Maxim N., Stallings, Christina L, Virgin, Herbert W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147835/
https://ncbi.nlm.nih.gov/pubmed/31959973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0633-0
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