UFMylation inhibits the proinflammatory capacity of interferon-γ–activated macrophages

Macrophages activated with interferon-γ (IFN-γ) in combination with other proinflammatory stimuli, such as lipopolysaccharide or tumor necrosis factor-α (TNF-α), respond with transcriptional and cellular changes that enhance clearance of intracellular pathogens at the risk of damaging tissues. IFN-γ...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Balce, Dale R., Wang, Ya-Ting, McAllaster, Michael R., Dunlap, Bria F., Orvedahl, Anthony, Hykes, Barry L., Droit, Lindsay, Handley, Scott A., Wilen, Craig B., Doench, John G., Orchard, Robert C., Stallings, Christina L., Virgin, Herbert W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817147/
https://ncbi.nlm.nih.gov/pubmed/33372156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011763118
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