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HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lymphatic dysfunction. The mechanisms that transduce the...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Boehme, Jason T., Morris, Catherine J., Chiacchia, Samuel R., Gong, Wenhui, Wu, Katherine Y., Kameny, Rebecca J., Raff, Gary W., Fineman, Jeffrey R., Maltepe, Emin, Datar, Sanjeev A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809484/
https://ncbi.nlm.nih.gov/pubmed/33446832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80882-1
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