Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease

The risk and progression of pulmonary vascular disease in patients with congenital heart disease is dependent on the hemodynamics associated with different lesions. However, the underlying mechanisms are not understood. Endothelin-1 is a potent vasoconstrictor that plays a key role in the pathology...

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Bibliographische Detailangaben
Veröffentlicht in:Pulm Circ
Hauptverfasser: Zhu, Terry, Chiacchia, Samuel, Kameny, Rebecca J., Garcia De Herreros, Antoni, Gong, Wenhui, Raff, Gary W., Boehme, Jason B., Maltepe, Emin, Lasheras, Juan C., Black, Stephen M., Datar, Sanjeev A., Fineman, Jeffrey R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238833/
https://ncbi.nlm.nih.gov/pubmed/32489641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020922118
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