Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease

The risk and progression of pulmonary vascular disease in patients with congenital heart disease is dependent on the hemodynamics associated with different lesions. However, the underlying mechanisms are not understood. Endothelin-1 is a potent vasoconstrictor that plays a key role in the pathology...

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Bibliografiske detaljer
Udgivet i:Pulm Circ
Main Authors: Zhu, Terry, Chiacchia, Samuel, Kameny, Rebecca J., Garcia De Herreros, Antoni, Gong, Wenhui, Raff, Gary W., Boehme, Jason B., Maltepe, Emin, Lasheras, Juan C., Black, Stephen M., Datar, Sanjeev A., Fineman, Jeffrey R.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238833/
https://ncbi.nlm.nih.gov/pubmed/32489641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020922118
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