Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease

The risk and progression of pulmonary vascular disease in patients with congenital heart disease is dependent on the hemodynamics associated with different lesions. However, the underlying mechanisms are not understood. Endothelin-1 is a potent vasoconstrictor that plays a key role in the pathology...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Zhu, Terry, Chiacchia, Samuel, Kameny, Rebecca J., Garcia De Herreros, Antoni, Gong, Wenhui, Raff, Gary W., Boehme, Jason B., Maltepe, Emin, Lasheras, Juan C., Black, Stephen M., Datar, Sanjeev A., Fineman, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238833/
https://ncbi.nlm.nih.gov/pubmed/32489641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020922118
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