Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease

The risk and progression of pulmonary vascular disease in patients with congenital heart disease is dependent on the hemodynamics associated with different lesions. However, the underlying mechanisms are not understood. Endothelin-1 is a potent vasoconstrictor that plays a key role in the pathology...

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Dettagli Bibliografici
Pubblicato in:Pulm Circ
Autori principali: Zhu, Terry, Chiacchia, Samuel, Kameny, Rebecca J., Garcia De Herreros, Antoni, Gong, Wenhui, Raff, Gary W., Boehme, Jason B., Maltepe, Emin, Lasheras, Juan C., Black, Stephen M., Datar, Sanjeev A., Fineman, Jeffrey R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238833/
https://ncbi.nlm.nih.gov/pubmed/32489641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020922118
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