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Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation

Vascular cell hyperproliferation and metabolic reprogramming contribute to the pathophysiology of pulmonary arterial hypertension (PAH). An important cause of PAH in children with congenital heart disease (CHD) is increased pulmonary blood flow (PBF). To better characterize this disease course we st...

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Bibliografski detalji
Izdano u:Am J Physiol Heart Circ Physiol
Glavni autori: Boehme, Jason, Sun, Xutong, Tormos, Kathryn V., Gong, Wenhui, Kellner, Manuela, Datar, Sanjeev A., Kameny, Rebecca Johnson, Yuan, Jason X.-J., Raff, Gary W., Fineman, Jeffrey R., Black, Stephen M., Maltepe, Emin
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114466/
https://ncbi.nlm.nih.gov/pubmed/27591215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00040.2016
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