Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation

Vascular cell hyperproliferation and metabolic reprogramming contribute to the pathophysiology of pulmonary arterial hypertension (PAH). An important cause of PAH in children with congenital heart disease (CHD) is increased pulmonary blood flow (PBF). To better characterize this disease course we st...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Boehme, Jason, Sun, Xutong, Tormos, Kathryn V., Gong, Wenhui, Kellner, Manuela, Datar, Sanjeev A., Kameny, Rebecca Johnson, Yuan, Jason X.-J., Raff, Gary W., Fineman, Jeffrey R., Black, Stephen M., Maltepe, Emin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114466/
https://ncbi.nlm.nih.gov/pubmed/27591215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00040.2016
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