Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation

Vascular cell hyperproliferation and metabolic reprogramming contribute to the pathophysiology of pulmonary arterial hypertension (PAH). An important cause of PAH in children with congenital heart disease (CHD) is increased pulmonary blood flow (PBF). To better characterize this disease course we st...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Boehme, Jason, Sun, Xutong, Tormos, Kathryn V., Gong, Wenhui, Kellner, Manuela, Datar, Sanjeev A., Kameny, Rebecca Johnson, Yuan, Jason X.-J., Raff, Gary W., Fineman, Jeffrey R., Black, Stephen M., Maltepe, Emin
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
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Call for Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114466/
https://ncbi.nlm.nih.gov/pubmed/27591215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00040.2016
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