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Disrupted NOS signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow

Associated abnormalities of the lymphatic circulation are well described in congenital heart disease. However, their mechanisms remain poorly elucidated. Using a clinically relevant ovine model of a congenital cardiac defect with chronically increased pulmonary blood flow (shunt), we previously demo...

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Détails bibliographiques
Publié dans:Am J Physiol Heart Circ Physiol
Auteurs principaux: Datar, Sanjeev A., Gong, Wenhui, He, Youping, Johengen, Michael, Kameny, Rebecca J., Raff, Gary W., Maltepe, Emin, Oishi, Peter E., Fineman, Jeffrey R.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967199/
https://ncbi.nlm.nih.gov/pubmed/27199125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00649.2015
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