DNA damage alters nuclear mechanics through chromatin reorganization

DNA double-strand breaks drive genomic instability. However, it remains unknown how these processes may affect the biomechanical properties of the nucleus and what role nuclear mechanics play in DNA damage and repair efficiency. Here, we have used Atomic Force Microscopy to investigate nuclear mecha...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: dos Santos, Ália, Cook, Alexander W, Gough, Rosemarie E, Schilling, Martin, Olszok, Nora A, Brown, Ian, Wang, Lin, Aaron, Jesse, Martin-Fernandez, Marisa L, Rehfeldt, Florian, Toseland, Christopher P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797048/
https://ncbi.nlm.nih.gov/pubmed/33330932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1202
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