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ATM and KAT5 safeguard replicating chromatin against formaldehyde damage
Many carcinogens damage both DNA and protein constituents of chromatin, and it is unclear how cells respond to this compound injury. We examined activation of the main DNA damage-responsive kinase ATM and formation of DNA double-strand breaks (DSB) by formaldehyde (FA) that forms histone adducts and...
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| Опубликовано в: : | Nucleic Acids Res |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705693/ https://ncbi.nlm.nih.gov/pubmed/26420831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv957 |
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