Chromium in Drinking Water: Sources, Metabolism, and Cancer Risks

Por Zhitkovich, Anatoly
Publicado em 2011

Regulation of DNA damage responses by mismatch repair

Por Zhitkovich, Anatoly
Publicado em 2010

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic and Chromium

Por Salnikow, Konstantin, Zhitkovich, Anatoly
Publicado em 2007

Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II) and cobalt(II)

Por Luczak, Michal W., Zhitkovich, Anatoly
Publicado em 2013

Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells

Por Luczak, Michal W., Zhitkovich, Anatoly
Publicado no Toxicol Appl Pharmacol (2017)

Mechanism of DNA-Protein Crosslinking by Chromium

Por Macfie, Andrea, Hagan, Elizabeth, Zhitkovich, Anatoly
Publicado em 2010

Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process

Por Wong, Victor, Armknecht, Susan, Zhitkovich, Anatoly
Publicado em 2012

Variation in Extracellular Detoxification Is a Link to Different Carcinogenicity among Chromates in Rodent and Human Lungs

Por Krawic, Casey, Luczak, Michal W., Zhitkovich, Anatoly
Publicado no Chem Res Toxicol (2017)

Reductive activation with cysteine represents a chromium(III)-dependent pathway in the induction of genotoxicity by carcinogenic chromium(VI).

Por Zhitkovich, Anatoly, Quievryn, George, Messer, Joseph, Motylevich, Zhanna
Publicado em 2002

Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G(2) phase by mismatch repair

Por Reynolds, Mindy, Stoddard, Lauren, Bespalov, Ivan, Zhitkovich, Anatoly
Publicado em 2007

Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolism

Por Guttmann, David, Poage, Graham, Johnston, Tatiana, Zhitkovich, Anatoly
Publicado em 2008

Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels

Por Reynolds, Mindy, Armknecht, Susan, Johnston, Tatiana, Zhitkovich, Anatoly
Publicado em 2012

p53 activation by Ni(II) is a HIF-1α independent response causing caspases 9/3-mediated apoptosis in human lung cells

Por Wong, Victor C., Morse, Jessica L., Zhitkovich, Anatoly
Publicado em 2013

Chromium(VI) causes interstrand DNA crosslinking in vitro but shows no hypersensitivity in crosslink repair-deficient human cells

Por Morse, Jessica L., Luczak, Michal W., Zhitkovich, Anatoly
Publicado em 2013

Monitoring Cr Intermediates and Reactive Oxygen Species with Fluorescent Probes during Chromate Reduction

Por DeLoughery, Zachary, Luczak, Michal W., Zhitkovich, Anatoly
Publicado em 2014

Proteasome activity is important for replication recovery, CHK1 phosphorylation and prevention of G2 arrest after low-dose formaldehyde

Por Ortega-Atienza, Sara, Green, Samantha E., Zhitkovich, Anatoly
Publicado no Toxicol Appl Pharmacol (2015)

Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduction: Implications for in Vitro Models and Toxicogenomics

Por Luczak, Michal W., Green, Samantha E., Zhitkovich, Anatoly
Publicado no Environ Health Perspect (2015)

Mismatch Repair Proteins Are Activators of Toxic Responses to Chromium-DNA Damage

Por Peterson-Roth, Elizabeth, Reynolds, Mindy, Quievryn, George, Zhitkovich, Anatoly
Publicado em 2005

XRCC1 Deficiency Sensitizes Human Lung Epithelial Cells to Genotoxicity by Crocidolite Asbestos and Libby Amphibole

Por Pietruska, Jodie R., Johnston, Tatiana, Zhitkovich, Anatoly, Kane, Agnes B.
Publicado em 2010

Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins

Por Ortega-Atienza, Sara, Rubis, Blazej, McCarthy, Caitlin, Zhitkovich, Anatoly
Publicado no Am J Pathol (2016)