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Mismatch Repair Proteins Are Activators of Toxic Responses to Chromium-DNA Damage

Chromium(VI) is a toxic and carcinogenic metal that causes the formation of DNA phosphate-based adducts. Cr-DNA adducts are genotoxic in human cells, although they do not block replication in vitro. Here, we report that induction of cytotoxicity in Cr(VI)-treated human colon cells and mouse embryoni...

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Detaylı Bibliyografya
Asıl Yazarlar: Peterson-Roth, Elizabeth, Reynolds, Mindy, Quievryn, George, Zhitkovich, Anatoly
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084304/
https://ncbi.nlm.nih.gov/pubmed/15831465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3596-3607.2005
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