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Mismatch Repair Proteins Are Activators of Toxic Responses to Chromium-DNA Damage
Chromium(VI) is a toxic and carcinogenic metal that causes the formation of DNA phosphate-based adducts. Cr-DNA adducts are genotoxic in human cells, although they do not block replication in vitro. Here, we report that induction of cytotoxicity in Cr(VI)-treated human colon cells and mouse embryoni...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084304/ https://ncbi.nlm.nih.gov/pubmed/15831465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3596-3607.2005 |
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