WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts

Recent studies in yeast have found that processing of DNA-double strand breaks (DSB) for recombination repair involves Sgs1 helicase. Human cells have five Sgs1 homologues with unknown selectivity and significance for repair of different DSB types. Here we examined the importance of WRN helicase in...

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Bibliographic Details
Main Authors: Zecevic, Alma, Menard, Haley, Gurel, Volkan, Hagan, Elizabeth, DeCaro, Rosamaria, Zhitkovich, Anatoly
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226781/
https://ncbi.nlm.nih.gov/pubmed/19652551
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