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Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolism

Although reductive metabolism of Cr(VI) always results in the production of Cr(III) and extensive Cr-DNA binding, cellular studies have indicated that different reduction processes are not equivalent in the induction of mutagenic events. Here we examined mutagenicity and formation of Cr-DNA damage b...

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Bibliografski detalji
Glavni autori: Guttmann, David, Poage, Graham, Johnston, Tatiana, Zhitkovich, Anatoly
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665875/
https://ncbi.nlm.nih.gov/pubmed/18808157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800265g
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