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Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolism
Although reductive metabolism of Cr(VI) always results in the production of Cr(III) and extensive Cr-DNA binding, cellular studies have indicated that different reduction processes are not equivalent in the induction of mutagenic events. Here we examined mutagenicity and formation of Cr-DNA damage b...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665875/ https://ncbi.nlm.nih.gov/pubmed/18808157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800265g |
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