DNA damage alters nuclear mechanics through chromatin reorganization

DNA double-strand breaks drive genomic instability. However, it remains unknown how these processes may affect the biomechanical properties of the nucleus and what role nuclear mechanics play in DNA damage and repair efficiency. Here, we have used Atomic Force Microscopy to investigate nuclear mecha...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: dos Santos, Ália, Cook, Alexander W, Gough, Rosemarie E, Schilling, Martin, Olszok, Nora A, Brown, Ian, Wang, Lin, Aaron, Jesse, Martin-Fernandez, Marisa L, Rehfeldt, Florian, Toseland, Christopher P
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797048/
https://ncbi.nlm.nih.gov/pubmed/33330932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1202
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