DNA damage alters nuclear mechanics through chromatin reorganization

DNA double-strand breaks drive genomic instability. However, it remains unknown how these processes may affect the biomechanical properties of the nucleus and what role nuclear mechanics play in DNA damage and repair efficiency. Here, we have used Atomic Force Microscopy to investigate nuclear mecha...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: dos Santos, Ália, Cook, Alexander W, Gough, Rosemarie E, Schilling, Martin, Olszok, Nora A, Brown, Ian, Wang, Lin, Aaron, Jesse, Martin-Fernandez, Marisa L, Rehfeldt, Florian, Toseland, Christopher P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797048/
https://ncbi.nlm.nih.gov/pubmed/33330932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1202
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