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USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair
How chromatin dynamics is regulated to ensure efficient DNA repair remains to be understood. Here, we report that the ubiquitin-specific protease USP11 acts as a histone deubiquitinase to catalyze H2AK119 and H2BK120 deubiquitination. We showed that USP11 is physically associated with the chromatin...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765148/ https://ncbi.nlm.nih.gov/pubmed/31504778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz726 |
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