DNA damage alters nuclear mechanics through chromatin reorganization

DNA double-strand breaks drive genomic instability. However, it remains unknown how these processes may affect the biomechanical properties of the nucleus and what role nuclear mechanics play in DNA damage and repair efficiency. Here, we have used Atomic Force Microscopy to investigate nuclear mecha...

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Bibliografiske detaljer
Udgivet i:	Nucleic Acids Res
Main Authors:	dos Santos, Ália, Cook, Alexander W, Gough, Rosemarie E, Schilling, Martin, Olszok, Nora A, Brown, Ian, Wang, Lin, Aaron, Jesse, Martin-Fernandez, Marisa L, Rehfeldt, Florian, Toseland, Christopher P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2020
Fag:	Genome Integrity, Repair and Replication
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7797048/ https://ncbi.nlm.nih.gov/pubmed/33330932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1202
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DNA damage alters nuclear mechanics through chromatin reorganization

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