FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs

Focal adhesion kinase (FAK) localizes to focal adhesions and is overexpressed in many cancers. FAK can also translocate to the nucleus, where it binds to, and regulates, several transcription factors, including MBD2, p53 and IL-33, to control gene expression by unknown mechanisms. We have used ATAC-...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Griffith, Billie G. C., Upstill-Goddard, Rosanna, Brunton, Holly, Grimes, Graeme R., Biankin, Andrew V., Serrels, Bryan, Byron, Adam, Frame, Margaret C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794255/
https://ncbi.nlm.nih.gov/pubmed/33420223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80111-9
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia