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Nuclear FAK and Runx1 cooperate to regulate IGFBP3, cell cycle progression and tumor growth

Nuclear focal adhesion kinase (FAK) is a potentially important regulator of gene expression in cancer, impacting both cellular function and the composition of the surrounding tumor microenvironment. Here we report in a murine model of skin squamous cell carcinoma (SCC) that nuclear FAK regulates Run...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Res
मुख्य लेखकों: Canel, Marta, Byron, Adam, Sims, Andrew H., Cartier, Jessy, Patel, Hitesh, Frame, Margaret C., Brunton, Valerie G., Serrels, Bryan, Serrels, Alan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126615/
https://ncbi.nlm.nih.gov/pubmed/28807942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0418
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