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FAK goes nuclear to control antitumor immunity—a new target in cancer immuno-therapy

Evading the antitumor immune response is important for the survival and progression of cancer. Recently, we identified an unexpected role for nuclear Focal Adhesion Kinase (FAK) activity in the control of tumor Treg levels and immune evasion by regulating chemokine and cytokine transcription in canc...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Serrels, Alan, Frame, Margaret C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839353/
https://ncbi.nlm.nih.gov/pubmed/27141405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1119356
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