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Signaling of the direction-sensing FAK/RACK1/PDE4D5 complex to the small GTPase Rap1
We recently reported that a complex between focal adhesion kianse (FAK) and the molecular scaffold RACK1 controlled nascent integrin adhesion formation and cell polarization, via peripheral recruitment of the cAMP - degrading PDE4D5 isoform. Here we review and extend these studies by demonstrating t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116620/ https://ncbi.nlm.nih.gov/pubmed/21686284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.1.15137 |
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