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Src-dependent autophagic degradation of Ret in FAK-signalling-defective cancer cells
We have recently described that autophagic targeting of Src maintains cancer cell viability when FAK signalling is defective. Here, we show that the Ret tyrosine kinase is also degraded by autophagy in cancer cells with altered/reduced FAK signalling, preventing its binding to FAK at integrin adhesi...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410392/ https://ncbi.nlm.nih.gov/pubmed/22732841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.92 |
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