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Quantitative in vivo imaging of the effects of inhibiting integrin signalling via Src and FAK on cancer cell movement; effects on E-cadherin dynamics

Most cancer related deaths are due to the development of metastatic disease and several new molecularly targeted agents in clinical development have the potential to prevent disease progression. However, it remains difficult to assess the efficacy of anti-metastatic agents in the clinical setting an...

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Detalhes bibliográficos
Main Authors: Canel, Marta, Serrels, Alan, Miller, Derek, Timpson, Paul, Serrels, Bryan, Frame, Margaret C., Brunton, Valerie G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079905/
https://ncbi.nlm.nih.gov/pubmed/21045155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1454
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