IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

Focal adhesion kinase (FAK) mediates tumor cell–intrinsic behaviors that promote tumor growth and metastasis. We previously showed that FAK also induces the expression of inflammatory genes that inhibit antitumor immunity in the microenvironment. Here, we identified a crucial, previously unknown rol...

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Vydáno v:Sci Signal
Hlavní autoři: Serrels, Bryan, McGivern, Niamh, Canel, Marta, Byron, Adam, Johnson, Sarah C, Mcsorley, Henry, Quinn, Niall, Taggart, David, Von Kreigsheim, Alex, Anderton, Stephen M, Serrels, Alan, Frame, Margaret C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128400/
https://ncbi.nlm.nih.gov/pubmed/29208683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan8355
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