IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

Focal adhesion kinase (FAK) mediates tumor cell–intrinsic behaviors that promote tumor growth and metastasis. We previously showed that FAK also induces the expression of inflammatory genes that inhibit antitumor immunity in the microenvironment. Here, we identified a crucial, previously unknown rol...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Serrels, Bryan, McGivern, Niamh, Canel, Marta, Byron, Adam, Johnson, Sarah C, Mcsorley, Henry, Quinn, Niall, Taggart, David, Von Kreigsheim, Alex, Anderton, Stephen M, Serrels, Alan, Frame, Margaret C
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128400/
https://ncbi.nlm.nih.gov/pubmed/29208683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan8355
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